Cardiac & neurological repair
The most scientifically exciting, and most overstated, thymosin beta-4 research is in the heart and nervous system.
The boldest claims, and the honest contradictions
The most scientifically exciting, and most overstated, thymosin beta-4 research is in the heart and nervous system. Two high-profile Nature papers reported that it protected injured mouse hearts and stimulated outgrowth from dormant heart-surface (epicardial) tissue. A 2011 paper went further and claimed new heart muscle, and a 2012 study then found that treatment after a heart attack did not turn epicardial cells into heart muscle.
This unit walks the cardiac story, the contradiction that followed, the neurological animal data, and where the human evidence stands: randomized cardiac trials, the largest of them negative overall.