Anti-inflammatory & remodeling

Calming inflammation without shutting it off

Repair stalls when inflammation never resolves. Thymosin beta-4 is studied for shifting that balance: in stimulated human corneal cells it lowered the level and activity of NF-κB, a switch for inflammatory genes, and a fragment released from it, Ac-SDKP, is described as anti-fibrotic.

This unit covers the NF-κB mechanism, the Ac-SDKP story, the cytokines involved, and the honest limits of this anti-inflammatory framing.