survodutide mastery course
Unit 2 of 12
Molecular Architecture
29 amino acids engineered for dual receptor activity and weekly dosing
Engineering a Dual Agonist
Survodutide starts from the 29-amino-acid glucagon backbone and introduces strategic modifications at key positions. These changes shift receptor selectivity, extend half-life through C18 fatty acid acylation, and produce a molecule capable of activating both GLP-1R and GCGR from a single weekly injection.
Interactive Structure Viewer
Explore the peptide backbone, modification sites, and acylation chemistry that define survodutide.
peptide structure viewer