neurotrophic mechanisms

how semax upregulates BDNF and NGF to support neuronal survival

neurotrophic factors are the core mechanism

The primary mechanism through which Semax exerts its neuroprotective and cognitive effects is upregulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). these neurotrophins activate TrkB and TrkA receptors, triggering cascades that promote neuronal survival, synaptic plasticity, and long-term potentiation.

BDNF pathway explorer

explore the interactive visualization for this unit.

BDNF pathway explorer

Knowledge Check

test your understanding of neurotrophic factor signaling.

Practice

apply the neurotrophic mechanisms before moving to cognitive effects.