Dosing & Administration

Titration schedule, injection technique, storage, and monitoring

Practical Dosing

Retatrutide is administered as a once-weekly subcutaneous injection with a gradual dose escalation to manage GI tolerability. The Phase 2 trial tested four dose tiers (1mg, 4mg, 8mg, 12mg) with a structured titration that started low and increased every four weeks. This unit covers the practical side: how to titrate, where to inject, how to store, and what to monitor.

Interactive Dosing Timeline

Step through the Phase 2 dose escalation protocol week by week, from starting dose through full maintenance at each tier.

interactive dosing timeline

Knowledge Check

Test what you've learned about retatrutide dosing and administration.

Practice Exercises

Reinforce your understanding.