reported effects beyond tanning

appetite suppression, sexual arousal, and why multi-receptor activation is a liability

more than pigmentation

because Melanotan II hits MC1R, MC3R, MC4R, and MC5R simultaneously, its reported effects extend well beyond skin darkening. appetite suppression via MC4R, sexual arousal via MC3R/MC4R, and exocrine changes via MC5R are all downstream consequences of non-selective melanocortin agonism. these are not side effects -- they are the predictable result of the molecule's receptor profile.

effects by receptor dashboard

map each reported effect back to the melanocortin receptor subtype that mediates it.

effects by receptor dashboard

Knowledge Check

test your understanding of non-pigmentation effects and receptor attribution.

Practice

apply the multi-receptor framework before moving to safety signals.