Dosing & Administration
This unit explains, for education only, the routes of administration and the entire published human dose record, so…
How MT-II is used, and why the confidence is misplaced
This unit explains, for education only, the routes of administration and the entire published human dose record, so you can read community discussion of MT-II critically. It is not a protocol, a dose, or a recommendation, and MT-II is not approved for human use.
The honest throughline is that confident online dosing numbers rest on almost no controlled human data. This unit prints no schedule and no worked dose calculation, precisely so you can see how little evidence sits beneath the certainty.
Key terms
The routes people use
MT-II is used by two main routes in the real world, and they differ enormously in how well they are understood. Injection is the route every clinical study in this course used, subcutaneous wherever the paper names the route; the nasal spray promoted on social media has no clinical study behind it in this course's sources. By mouth, the only figure here is a 4.6% bioavailability in rats, from a preformulation paper weighing oral delivery.
The irony is sharp: the newly popular route is the least understood. No human study in this course's sources measured MT-II exposure from a nasal product, and the one analysis of sprays here, a TGA safety advisory of 17 August 2026, estimated 22 to 54 mg of melanotan II across five seized bottles all labelled 30 mg, so a spray delivers an unknown amount of an inconsistently dosed product. Australian consumer journalism, last updated 11 March 2025, reported tanning nasal sprays with illegal ingredients openly advertised and sold online there, at around $100 a bottle, with a TGA spokesperson quoted saying every form of these products carries significant health risks. Any confident nasal-spray protocol is certainty the evidence cannot support.
This unit is education only and not medical advice. Nothing here is a protocol or a recommendation to use Melanotan II by any route.