melanotan ii mastery course
Unit 7 of 11

dosing & administration

community-reported protocols, reconstitution math, and practical administration for harm reduction education

harm reduction, not endorsement

This unit documents community-reported dosing protocols for educational purposes only. None of this constitutes medical advice. No dosing regimen described here has been validated by clinical trials for the use cases discussed. Product quality from unregulated sources varies and is a significant risk factor.

The goal is harm reduction. People use Melanotan II regardless of regulatory status, and documenting what the community actually does -- with appropriate context -- is more responsible than leaving them to unvetted forum posts.

Reconstitution Calculator

Calculate concentration and syringe units for common MT-II vial sizes. Adjust the bacteriostatic water volume and vial content to see how concentration changes and what each tick mark on an insulin syringe represents.

reconstitution calculator

key numbers

reconstitution and dosing parameters from community-reported protocols.

5-10 mg
common vial sizes (lyophilized powder)
0.25-0.5 mg
typical community-reported dose per injection
~1-2 hours
half-life (short, requires frequent dosing)
SC
subcutaneous injection (self-administered)
This unit documents community-reported protocols for harm reduction education only. None of this constitutes medical advice. No dosing regimen described here has been validated by clinical trials. Product quality from unregulated sources is a significant risk factor -- heavy metals, endotoxins, incorrect doses, and mislabeled peptides have been documented in gray market products.

key terms

dosing and reconstitution vocabulary for this unit. tap to expand.

R reconstitution preparation
Dissolving lyophilized (freeze-dried) peptide powder in bacteriostatic water to create an injectable solution. The volume of water added determines the concentration. For a 10 mg vial with 2 mL water, each 0.1 mL (10 units on an insulin syringe) contains 0.5 mg.
B bacteriostatic water solvent
Sterile water containing 0.9% benzyl alcohol as a preservative. Prevents bacterial growth after reconstitution, allowing multi-dose use from a single vial. Reconstituted MT-II stored refrigerated at 2-8C is generally considered stable for 3-4 weeks.
L loading phase protocol
Community-reported initial dosing period where MT-II is administered daily or near-daily to build melanocyte activation. Typically 0.25-0.5 mg daily for 1-3 weeks, combined with UV exposure. Followed by a lower-frequency maintenance phase.
M maintenance phase protocol
Community-reported period after the loading phase where injection frequency drops to 1-2 times per week. The goal is to sustain the pigmentation achieved during loading. Some users report maintaining tan with even less frequent dosing.
I insulin syringe equipment
A 1 mL syringe marked in 100 units (each unit = 0.01 mL). The standard tool for subcutaneous peptide injection. At a concentration of 5 mg/mL (10 mg vial + 2 mL water), 5 units on the syringe equals 0.25 mg of MT-II.

reconstitution reference

how water volume changes concentration and syringe units for a standard 10 mg vial.

1.0 mL water
concentration: 10 mg/mL. a 0.25 mg dose = 2.5 units on the syringe. 40 doses per vial. very concentrated -- small volume errors have large dose impact.
2.0 mL water
concentration: 5 mg/mL. a 0.25 mg dose = 5 units on the syringe. 40 doses per vial. most common reconstitution volume in community reports.
3.0 mL water
concentration: 3.3 mg/mL. a 0.25 mg dose = 7.5 units on the syringe. 40 doses per vial. more forgiving for dose accuracy but larger injection volumes.