melanotan ii mastery course
Unit 4 of 11
chemistry, structure, and pharmacokinetics
a 7-amino-acid cyclic peptide with a half-life that matters
designed for potency, not selectivity
Melanotan II's cyclic heptapeptide structure was engineered for metabolic stability and high receptor binding potency. the lactam bridge that constrains its conformation is the same structural feature that eliminated the receptor selectivity of its linear ancestor.
structure comparison tool
compare the structural features of alpha-MSH, afamelanotide (MT-I), and Melanotan II side by side.
structure comparison tool