FOXO4-DRI mastery course
Unit 5 of 11
Aging & animal models
The images that made FOXO4-DRI famous came from mice: aged animals reported to have fuller fur, to be more responsive…
The mouse experiments that started it all
The images that made FOXO4-DRI famous came from mice: aged animals reported to have fuller fur, to be more responsive to gentle handling, and to show lower plasma kidney markers after a few pulses of peptide. These are the results everyone quotes, so it is worth examining exactly what was done, what was measured, and what the experiments do and do not prove.
This unit walks through the Baar 2017 aged-mouse work in detail, honestly separating the genuinely impressive from the frequently over-stated.