How DSIP works

Many proposed mechanisms, no confirmed target

If DSIP has a single receptor, no one has found it. Instead, the studies in this unit tie it to several neurotransmitter and hormone pathways at once, which is why this course reads it as a systems-level modulator: GABA and glutamate balance in rat neurons, opioid signalling in rat brainstem slices, the stress axis in rats, and the pineal-melatonin system in rat pineal tissue.

This unit walks each proposed mechanism, weighs how strong the evidence is, and explains why "broad modulator with no validated target" is both the most honest description and the reason DSIP is so hard to develop.