Dihexa mastery course
Unit 2 of 10

Chemistry & structure

Dihexa is a piece of engineering. Starting from angiotensin IV, the Harding lab kept only the two-residue core thought…

How dihexa is built from angiotensin IV

Dihexa is a piece of engineering. Starting from angiotensin IV, the Harding lab kept only the two-residue core thought to matter for cognition and added two fatty caps to defeat the enzymes that normally chew peptides apart in minutes.

This unit walks the structure: the angiotensin IV lineage, the capped design, the molecular diagram, and why the pharmacokinetic claims you will read are mostly unmeasured in humans.

Key terms

From angiotensin IV to dihexa


The molecular structure


Engineering for survival


Small enough to reach the brain?


Correcting the "hexapeptide" label


The pharmacokinetics gap