CJC-1295 mastery course
Unit 4 of 12
The GH and IGF-1 axis
CJC-1295 never touches muscle or fat directly. It works one step upstream, on the pituitary GHRH receptor, prompting yo…
One receptor upstream, a cascade downstream
CJC-1295 never touches muscle or fat directly. It works one step upstream, on the pituitary GHRH receptor, prompting your own gland to release growth hormone in its natural way. That released GH then travels to the liver and drives IGF-1, the hormone that actually carries out most of the effects people care about.
This unit maps the whole axis: where the receptor sits, how the signal runs inside a pituitary cell, how the liver relays it into IGF-1, and how the body feeds back to keep the system in check. Understanding this upstream position is the key difference from injecting growth hormone itself.