tb-500 mastery course
Unit 2 of 12

molecular structure

the 43-amino-acid sequence, three functional domains, and what makes the LKKTET motif unique

43 Amino Acids, Three Domains

TB-500 is the 43-residue sequence of thymosin beta-4: an N-terminal signaling stretch, the LKKTET actin-binding motif, and a C-terminal tail.

the label technically names a 7-residue LKKTET-Q heptapeptide, but vendors ship the full TB4 chain under it.

43 aa
full TB4 length
LKKTET
actin-binding motif
Ac-SDKP
N-terminal cleavage product
3
functional domains

meet the molecule

click any residue to see its role.

TB-500 / thymosin beta-4 domain map

Explore the Structure

tap a domain to see its role.

interactive structure viewer