immunopeptide origins

how an immune peptide became a brain drug

from tuftsin to selank

tuftsin is a four-amino-acid fragment of immunoglobulin G that stimulates phagocytosis. Russian researchers extended it with Pro-Gly-Pro, and the result was a peptide that crossed into the CNS and modulated anxiety circuits. this unit traces that transformation.

interactive explorer

explore the key concepts for this unit.

immunopeptide origins explorer

Knowledge Check

test your understanding of tuftsin biology and selank design.

Practice

apply the peptide design concepts before moving to mechanisms.