chemistry and pharmacokinetics

Thr-Lys-Pro-Arg-Pro-Gly-Pro -- seven residues, two origins

seven amino acids, carefully arranged

selank's sequence (Thr-Lys-Pro-Arg-Pro-Gly-Pro) combines the first four residues of tuftsin with a stabilizing Pro-Gly-Pro tail. this unit explores the chemistry, structural comparison to tuftsin and semax, and the intranasal pharmacokinetic profile.

interactive explorer

explore the key concepts for this unit.

chemistry and pharmacokinetics explorer

Knowledge Check

test your understanding of selank chemistry and PK.

Practice

apply the structural concepts before moving to safety.