The Genome Reset

How a cell-line analysis created the 32.1% headline, and what it does not prove in humans

Rewriting the Genetic Playbook

In 2014, researchers reported a Connectivity Map analysis often summarized as GHK-Cu modulating 32.1% of 13,424 analyzed genes -- just over 4,000 signals in one cell-line dataset. That is intriguing systems-biology data, but it is not the same as proving GHK-Cu rewrites 32% of genes throughout the human body.

interactive gene heatmap

Knowledge Check

Test what you've learned about GHK-Cu's gene expression effects.

Practice Exercises

Reinforce your understanding.